::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

LOW DOSE TRAMADOL VERSUS KETAMINE: WHICH IS MORE EFFECTIVE TO COUNTER PREOPERATIVE SHIVERING DUE TO SPINAL ANESTHESIA AMONG ABDOMINAL SURGERIES PATIENTS

AUTHORS:

Dr. Safina Babar, Dr. Rauha Ahmad, Dr. Maryam Suryya Zafar

ABSTRACT:

Objective: The objective of this research was to draw a comparison between prophylactic efficacy with low dose tramadol and ketamine to prevent shivering of the patients in the course of spinal anaesthesia while experiencing abdominal surgeries. Material and methods: This comparative research was carried out at Services Hospital, Lahore from September 2017 to April 2018. We enrolled 64 patients of both genders having physical status (ASA) with Class I & II in the bracket of (18 – 50) years. These patients were about to experience an elective lower abdominal surgery in a supine position. The nature of procedure was general which included hernioplasty, cystolithotomy, appendectomy and gynaecological procedures including vaginal and abdominal hysterectomy; whereas, we did not included unwilling patients, blood transfusion requirement cases, pregnant patients, blood product requirement patients, patients with BMI above 30 (Obese), coagulopathy (platelets count under 80,000), having abscess at injection site, Hemodynamically unstable patients (BP under 100 mmHg) and all those patients who were allergic to local anesthetics. After fulfilling inclusion criteria, the patients were distributed randomly in two groups respectively Group – K & T. Results: The mean age of Group – K was (28.13 ± 6.19) and mean age of Group – T was (28.41 ± 5.97) years. In terms of efficacy of both the groups the efficacy of Group – K was reported in 6 patients (18.75%); whereas, in Group – T the efficacy was reported in 15 patients (46.88%). The remaining cases without efficacy in both groups were respectively in Group – K as 26 (81.5%) and in Group – T as 17 (53.12%). P-Value was taken as (0.01) that shows a significant difference. Conclusion: Outcomes suggest that while making a comparison of both the groups about the effectiveness of prophylactic low dose tramadol with ketamine with tramadol to prevent shivering of the patients in the course of spinal anaesthesia while experiencing abdominal surgeries; tramadol is less effective than Ketamine. The effectiveness of Ketamine is superior to manage an onset of shivering among patients. Keywords: Abdominal Surgery, Prophylactic, Spinal Anesthesia, Ketamine, Low Dose, Tramadol and Shivering.