::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

ANALYSIS OF OXIDATIVE STRESS OF 1 TO 5 YEARS OF CHILDREN SUFFERING FROM JAUNDICE

AUTHORS:

Dr Iqra Amjad, Dr Rabiya Illyas, Dr Shoaib Ahmed

ABSTRACT:

Aim of the study: The basic aim of the study is to find the level of antioxidant in children (age 1-5 years) who is suffering from jaundice. Methodology of the study: This cross-sectional study was conducted in Jinnah Hospital Lahore during March 2019 to November 2019. All the data was collected with the permission of ethical committee of hospital and with the permission of parents. We collected the data from all those patients who was suffering from jaundice fever. 5cc blood was drawn from vein for the analysis of TAC from blood serum. Results: Serum MDA, GSH, GPx, Catalases and SOD concentrations were significantly lower after phototherapy than before it (p < 0.05). Conversely, serum TOS, lipid hydroperoxide levels were significantly lower than normal values. There were significantly positive correlations between serum total MDA and GSH. Conclusion: jaundice fever in children and serum TAC. The lowest values shows that antioxidants are the important serum biomarker in the prognosis of jaundice.