ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

CASE STUDY ON EWING SARCOMA

Nadeem Khokhar, Ms. Hajra Sarwar, Mr. Muhammad Afzal

Ewing’s sarcoma is the 2nd most common primary sacral tumor. Ewing’s sarcomas are rare, aggressive tumors with a tendency concerning recurrence subsequent resection and early metastasis. Although peak incidents are between the ages of 10 and 20 years, patients of younger or older age account for almost 30% of the cases. We report the case of a 37-year-old healthy male who presented with an 8-month history of pain in his right posterior thigh that was unable to be comforted by non-steroidal anti-inflammatory medicine and physical therapy. Magnetic resonance imaging shown an irregular right presacral mass and core needle biopsy shown a small, round blue cell neoplasm. Staging workup was normal and an open biopsy was positive for the ES translocation. The patient was treated with 5 cycles of vincristine, adriamycin and cytoxan with mesna rescue, alternating with ifosfamide and etoposide. 4 month post-treatment the patient presented with a recurrent tumor. This case emphasizes the importance of timely establishment of initial diagnosis, early metastasis in treatment responsive patients and under-utilization of positron emission tomography-computed tomography (PET-CT) during the treatment to detect sub-clinical metastasis. Doctor changed the chemotherapy medicines to cyclophosphamide and carboplatin after reoccurrence of tumor.

FULL TEXT