- CODEN : IAJPBB
- issn 2349-7750
TITLE:
ALTERATION OF COAGULATION PROFILE IN MALARIA PATIENTS AND ITS CORRELATION WITH DEGREE OF PARASITEMIA.
AUTHORS:
Dr Roman Abbas,Dr Farrukh Zubair,Dr Amina Sadia
ABSTRACT:
Worldwide 3.2 million people are prone to malaria disease caused by Plasmodium species including Plasmodium falciparum and Plasmodium vivax while P. falciparum is the leading cause of deaths due to abrupt development of infection along with severe complications. It is known as the fifth leading cause of infectious diseases. The hold on the disease seemed to be difficult due to the ability of a parasite to create resistance in response to drugs and almost 85% reported cases of malaria were caused by falciparum species which is mostly found in the warmer and moist areas of the globe. This study considered the 100 patients and obtained repercussions of malarial patients indicate that 35.9% of cases of P. falciparum and 64.1 % cases of malaria were due to P.vivax. The mean values of age for patients and the control group was 25.35 ± 14.4 years. As the p-value for coagulation profile including APTT, PT, and d dimer was greater than 0.05. The platelet counts were measured both in P. vivax and P. falciparum malaria patients correlated with the degree of parasitemia as the P-value is less than 0.001 while the degree of correlation r = 0.894. Coagulation profile for P. vivax patients shows the normal PT and APTT while greater PT and APTT values in infected patients of P. falciparum were correlated with the degree of parasitemia as r = 0.0892. The percentage base on determining parasitic load was 53.3% of patients with a mild degree of parasitemia, 29.3% with moderate, and 17.4% suffered from severe parasitemia. Most coagulation abnormalities have risen because of liver involvement.
FULL TEXT
<Approved Journal
NLM ID:101711216 [Serial]
Included in EuroPub database
ICV 2015 - 61.16
Indexed In
S.J Impact Factor:7.157
cosmos Impact Factor:4.153
ICMJE Recommendations
IP Indexing Impact Factor: 2.76
Cover Page
