::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

A CROSS SECTIONAL STUDY TO DEFINE THE STATE OF VITAMIN D3 IN HEALTHY PERSONS

AUTHORS:

Dr Shujaat Hussain, Dr Shoaib Hameed Lone, Dr Jamil Alam

ABSTRACT:

Objectives: The aim of our study was to Define the deficiency of vitamin D3 and inefficiency in clinically asymptomatic and seemingly in healthy young persons. Study Design: A cross sectional study. Study and Time Duration: This study was conducted in Department of Medicine, Benazir Bhutto hospital (BBH) Rawalpindi for the duration of one year starting from July, 2019 to June, 2020. Methodology: According to our study criteria we selected the sample of 100 volunteer participants in which male sample was 57 and female sample was 43. We collected 5ml venous blood in a disposable syringe. We use standard laboratory procedures to estimate phosphate, serum calcium, serum creatinine and blood urea. Vitamin D3 is detected by ARCHITECT I 1000 system. SPSS 20 was used for analysis of data. Results: Serum Calcium and Phosphate were noted as3.23±0.85 and 3.25±0.80 mg/dl with P-value equal to 0.710 and 8.76±1.11, 9.20±0.2 mg/dl with P-value equal to 0.036 in male and female subjects respectively. Vitamin D3 (mean± SD) in male and female was noted as 23.0±8.24 and 27.19±14.13 ng/dl (P=0.006). Vitamin D3 (mean± SD) of total study population was noted as 24.80± 11.29 ng/ml. Frequency of vitamin D3 deficiency, insufficiency and sufficiency noted in 45%, 32% and 23% respectively (P=0.0001). Conclusion: The present study showed that vitamin D3 deficiency and insufficiency in 77% of young apparently healthy and clinically asymptomatic adults. Normal vitamin D3 levels were noted in only 23% of subjects. Furthermore, studies are recommended and vitamin D3 supplements should be described by clinicians. Key words: Iron, TIBC, Ferritin, Helicobacter Pylori, vitamin D3.