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PHYTOCHEMICAL SCREENING AND ANTI HYPERLIPIDEMIC ACTIVITY OF METHANOLIC EXTRACT OF ARGYREIA NERVOSA IN ALBINO RATS

Shilpa Reddy. K , Dr. P . Polireddy, Dr. Vivek V. Byahatti

Argyreia speciosa (Linn. f.) (Family: Convolvulaceae, Synonyms: Argyreia nervosa) is used in the traditional Ayurvedic systems of medicine as well as in local health folklore. It is commonly known as Vidhaara in Hindi and Hawaiian Baby Woodrose and Elephant creeper in English. It is the large climber and seen throughout India up to an altitude of 500 m. A. speciosa possess various pharmacological activity such as anti-aging, gastroprotective, analgesic & anti-inflammatory, aphrodisiac, antiviral, antidiabetic, anticonvulsion, antioxidant, antidiarrheal, antiulcer, central nervous system depressant, nematocides, nootropic, anticancer and many more. Apart from this numerous phytoconstituents have been isolated from A. speciosa.In present study evaluated phytochemical screening and anti-hyperlipidaemic activity. Phytochemical testing of the remove reveals the visibility of chemical components like Alkaloids, steroids, fixed oils, cardio tonic aglycones, flavonoids, saponins, carbohydrates, healthy proteins, resins. Severe OECD guide line no. 423, ED50 value was discovered to be 200mg/kg and also 400mg/kg.Anti Hyperlipidaemic activity was done by regimen caused technique. In today plasma HDL-cholesterol with a concomitant percent decrease from various other lipid was observed. It can be wrapped up from the here and now data that the levels of overall product cholesterol, triglyceride and also MDA which are really elevated in high fat diet regimen, can be lowered substantially with Argyreia nervosa and also antioxidant parameters SOD, GSH, Catalase which are actually can be increased significantly with Argyreia nervosa. Atherogenic index which in fact raised in atherogenic diet can be decreased considerably with Argyreia nervosa and also a very good % defense was seen with Argyreia nervosa and also basic medicineFrom this we can wrap up that the essence (Argyreia nervosa) Showed the anti-Hyperlipidaemic activity. KEYWORDS: Argyreia nervosa, Methanolic extract, Phytochemical screening, Anti- Hyperlipidemic Activity

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