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MEASLE’S COMPLICATIONS IN ACUTE PHASE IN PCM CHILDREN, PROSPECTIVE STUDY IN A TERTIARY CARE HOSPITAL

Prof. Dr Jalaluddin Akber, Dr. Naseeb Ullah, Dr. Arshad Hamid, Dr. S. Zafar Mehdi,Dr. Tahira Saeed ,Dr. Saleem Ahmed

Abstract: Objective: To determine measle’s complications in acute phase in PCM children, prospective study in a tertiary care hospital Plae and duration of study: Department of Peadiatrics Medicine Baqai Medical Hospital Karachi, from1st July 2017 to 30th June 2018. Study Design; A cross-sectional study Methodology: In this study, 100 PCM children between 12 and 60 months of age with PCM classification modified GOMEES clssification grade 1, 2 and 3 and diagnosed as measls using WHO criteria were included after ethical approval and informed and written consent. All those had not given informed consent and children with malignancy or metastatic disease were excluded in this study. Brief history was taken, clinical examination was done, and laboratory investigations were done to access the outcome i-e complications of measles in PCM children. Result: Total of 100 children with protein calorie malnutrition were included. 58 children (58%) were males & 42 (42%) were females with the mean age was 29.49+17.597 months. 25 patients (25%) had history of vaccination with measles vaccine and 75 (75%) were not vaccinated with measles vaccine and only one child (1%) had history of vaccination with MMR vaccine. Complications of measles were pneumonia in 80 (80%), acute gastroenteritis in 38(38%), dysentery in 18 (18%), otitis media in 29(29%), vitamin A deficiency in 49(49%), sepsis in 25(25%) and encephalitis in 6(6%). Conclusion: Pneumonia is the major complication in PCM patients with measles followed by diarrhea. Also there is high proportion of PCM children that are not vaccinated and also high proportion of vaccinated PCM children who did not complete the vaccination schedule which is a matter of concern for health planners. Key Words: Measles; Complications; Vaccination, PCM children, Prevention.

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