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COMPARISON OF EFFECT OF EARLY CORD CLAMPING WITH UMBILICAL CORD MILKING ON THYMIC SIZE AMONG PRE-TERM INFANTS

Dr. Muhammad Yasir Aslam, Dr Faria Ambreen, Dr. Nazia Bibi

Objectives: The research objective is the comparison of early cord clamping and umbilical cord milking effect on the thymic size, and neonatal morbidity/mortality among preterm infants. Methods: The study method is a controlled randomised, prospective and double-blind that we conducted in Mayo Hospital, Lahore (September 2018 to March 2019). We divided women, who delivered in less than 32 weeks, into two groups, Group-A (umbilical cord milking) and Group-B (early cord clamping). Our experienced radiologist performed Ultrasonographic evaluation in each new-born within the first day of life. We estimated thymic size in-line with literature. We analyzed all data using SPSS. Results: There were 38 and 37 patients in Group-A and Group-B respectively with insignificant (P=0.213) higher Haemoglobin level in Group-A. In Group-A, the absolute neutrophil count was lower than Group-B with P= 0.017 however the difference between neonatal mortality/morbidity was insignificant (P> 0.05). Conclusion: We did not find any association of UCM with TS within the first 24-hours of newborn's life. Keywords: Thymic Size (TS), Umbilical Cord Milking (UCM), Umbilical Cord (UC), Acute Thymic Involution (ATI), Early Cord Clamping (ECC), Premature Infant (PI), Full-Term Infants (FTI), Pre-Term Infant (PTI), and Placental Transfusion (PT).

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