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TITLE:

EVALUATION OF THE GLYCEMIC CONTROL AFTER TREATMENT WITH NPH AND GLARGINE INSULIN IN THE PATIENTS SUFFERING FROM TYPE-1 DIABETES

AUTHORS:

Dr Anum Mehreen, Dr Mubasit, Dr Ali Shan Liaqat

ABSTRACT:

Objective: The aim of this research work is to assess the glycemic control with a combine treatment of glargine insulin & NPH. Methodology: This study was a prospective research work conducted on 10 patients suffering from Type-1 diabetes. We assessed the control of the glucose level & hypoglycemic episodes with a combine treatment through insulin NPH & glargine. We recorded at baseline the HbA1C, fasting plasma glucose, PPG (post-prandial glucose) and glucose level of blood on the arrival of the children as well as after 2 months & six months. Results: The average HbA1C decreased from 7.68% to 5.8%, the prevalence of the hypoglycemia decreased from 1.78% to 1.18%, average FBG (Fasting Blood Glucose) decrease 119.0 mg/dl to 106.0 mg/dl & average glucose of blood on their arrival from school decreases 285.58 to 165.28 mg/dl over a six-month period of observation. Conclusion: This treatment is very helpful with better results with low level of blood glucose at the time of the arrival from the school as well as no enhancement in the hypoglycemic episodes. Keywords: Glycosylated Hemoglobin, Type 1 Diabetes, Insulin Glargine, Prevalence, Glucose, Follow-Up.

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