Volume : 10, Issue : 02, February – 2023
Title:
16.FORMULATION AND EVALUATION OF THE LORNOXICAM SUSTAINED RELEASE TABLETS BY USING NATURAL POLYMERS
Authors :
Miryala Manjula, D.Rajkumar
Abstract :
The main aim of the study formulation and evaluation of the lornoxicam sustained release tablets by using natural polymers. Definition and assessment of the continued delivery tablets of the Lornoxicam. For improvement of the tablets diverse excipients are utilized. The utilized avrious excipients are the karayagum, sodium alginate , pvpk30, Mg.sterate, Talc, MCC utilized as the diluents, Mg.sterate utilized as the ointments. Powder is utilized as Glidant. The plan is created by the utilizing direct pressure method.The detailing is set up by utilizing distinctive excipients .The excipients are hpmc and xanthin gum in different arrangements for medication to deliver in 10hrs. The pre pressure boundaries are done, for example, the mass thickness ,tap thickness, compressability file, Hauners proportion, Angle of rest. The all boundaries are gone under inside range great stream. The post pressure boundaries are done, for example, the saddle, thickness, weight variety, friability, breaking down. The assessment boundaries of theoptimised plan F8 tablets esteems.The weight variety of network tablets, 4 00mg. The hardness of the network tablets, 3.1(Kg/cm2).Thickness of the network tablets, 2.50mm. Breaking down of the framework tablets,25 mins. Friability of the network tablets, 0.256 % . In-vitro tranquilize disintegration investigations of the oral dispersible tablets, 98.65% . The all boundaries go under adequate standards inside scope of limts. The In-vitro medicate discharge examines are finished by USP-II mechanical assembly paddle strategy. The improved definition F9gives the drag out delivery upto 10hrs the medication discharge
Keywords: Formulation, Evaluation, Lornoxicam, Sustained Release Tablets, Natural Polymers
Cite This Article:
Please cite this article in press Miryala Manjula et al, Formulation And Evaluation Of The Lornoxicam Sustained Release Tablets By Using Natural Polymers., Indo Am. J. P. Sci, 2023; 10 (02).
Number of Downloads : 10
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