Volume : 10, Issue : 02, February – 2023

Title:

34.STUDY TO EVALUATE THE MINIMUM INHIBITORY CONCENTRATION TRENDS OF CEFTRIAXONE AND CIPROFLOXACIN IN BLOOD CULTURE OF PEDIATRIC PATIENTS SUFFERING FROM TYPHOID FEVER IN MAX SUPER SPECIALTY HOSPITAL, PATPARGANJ, NEW DELHI – A RETROSPECTIVE STUDY

Authors :

Akansha Bhadouria, Sarika Chaturvedi, Mamta Dubey, Deeksha Shakya, Abhishek Tiwari, Shilpi Chaturvedi

Abstract :

Enteric fever caused by Salmonella enterica continues to be a major public health problem worldwide. In the last decade, ceftriaxone and ciprofloxacin have become the drugs of choice for treating enteric fever caused bySalmonella enteric serovar typhi. A retrospective study to understand the prevalence and evolving the minimum inhibitory concentration trends of ceftriaxone and ciprofloxacin . A total of 100 blood samples were collected from patients attending inpatient and outpatient departments of of pediatric patients suffering from typhoid fever at MSSH, Delhi from May 2012 to December 2013.Since enteric fever is endemic in India, accurate drug susceptibility surveillance is crucial to ensure empiric management of enteric fever is appropriate. This retrospective study aimed to evaluate the minimum inhibitory concentration trends of ceftriaxone and ciprofloxacin in blood culture of pediatric patients suffering from Typhid fever in Max Super Specialty Hospital, New Delhi, India
Keywords-Typhoid fever, ciprofloxacin, pediatric patients, retrospective study.

Cite This Article:

Please cite this article in press Akanksha Bhadouriaet al.,Study To Evaluate The Minimum Inhibitory Concentration Trends Of Ceftriaxone And Ciprofloxacin In Blood Culture Of Pediatric Patients Suffering From Typhoid Fever In Max Super Specialty Hospital, Patparganj, New Delhi – A Retrospective Study.,Indo Am. J. P. Sci, 2023; 10 (02).

Number of Downloads : 10

References:

1. Kliegman RM, Behrman RE, Jenson HB, Stanton BF. Nelson’s text book of pediatrics. 18th ed. Saunders: New York: Elsevier, 2008: P. 1186-90.
2. Park K. Textbook of preventive and social medicine. 17th ed. Jabalpur: BanarsidasBhonet.
3. Publishers; 1999: p/178-81.
4. Gupta MC, Mahajan BK. Text book of preventive and social medicine. 3rd ed. New Delhi: Jaypee; 2005: p. 202-5.
5. 4. Crump JA, Mintz ED. Global trends in Typhoid and paratyphoid fever. Clin Infect Dis 2010; 50:241-6.
6. Merican I. Typhoid fever: present and future. The Medical Journal of Malaysia 1997; 52:299—308.
7. Ivanoff B, Levine MM, and Lambert PH. Vaccination against typhoid fever: present status. Bull WHO 1994; 72:957—71.
8. 7. Ahmad KA, Khan LH, Roshan B, Bhutta ZA. A 12 year clinical experience with paediatric salmonellosis from an endemic population in Karachi. The International Society for Infectious Diseases Meeting, Argentina, April 2000.
9. Background document: The diagnosis, treatment and prevention of typhoid 2. Fever. Geneva: WHO; 2003.
10. Acharya IL, Lowe CU, Thapa R, Gurubacharva VL, Shrestra MB, Cadoz M,
11. Arora RK, Gupta A, Joshi NM, Kataria VK, Lall P, Anand AC. Multidrug resistant typhoid fever: study of an outbreak in Calcutta. Indian Pediatr 1992; 29:61—6.
12. Saha SK, Saha SK. Antibiotic resistance of Salmonella typhi in Bangladesh. J AntimicrobChemother 1994; 33:190—1.
13. Sharma J, Malakar M. Distribution of typhoid fever in different rural and urban areas of Lakhimpur district of Assam. International journal of Research.2013;1(3): 109-114.
14. Kidgell C, Reichard U, Wain J, Linz B, Torpdahl M, Dougan G, Acthman M. S. typhi, the causative agent of typhoid feveris approximately 50,000 years old, infection, Genetic and evolution .2(2002):39-45.
15. Ochiai RL, Acosta CJ, Danovaro-Holliday MC, Maiqing D, Bhattacharya SK, Agtini MD, Bhutta ZA, Canh DG, Ali M, Shin S, Wain J, Page AL, Albert MJ, Farrar J, Abu-Elyazeed R, Pang T, Galindo CM, Seidlein LV, Clemens JD. A study of typhoid fever in five Asian countries: disease burden& implementation for controls.2008; 86; 260-268.