Please cite this article in press Sapna Pandey et al, Pregnancy Complication And Role Of Lifestyle Modification In Women With Polycystic Ovary Syndrome., Indo Am. J. P. Sci, 2023; 10 (04).

1. Polycystic Ovary Syndrome: A woman’s guide to identifying and managing PCOS, Dr. John Eden; 2005:1.
2. Osman NN, Alsahfi SA, Alshubaily F. Effectiveness of Aqueous Extract of Fenugreek Seeds and Flaxseed on Polycystic Ovarian Syndrome in Female Rats. Int. J. Pharm. Res. Allied Sci. 2019;8(4):42-54.
3. Polycystic Ovary Syndrome: A woman’s guide to identifying and managing PCOS, Dr. John Eden; 2005:4.
4. Adams J, Polson DW, Franks S. Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism. Br Med J (Clin Res Ed) 1986;293:355-9
5. Balen A. Pathogenesis of polycystic ovary syndrome–the enigma unravels? Lancet 1999; 354:966-7 6
6. Michelmore KF, Balen AH, Dunger DB, Vessey MP. Polycystic ovaries and associated clinical and biochemical features in young women. Clin Endocrinol (Oxf) 1999;51:77986
7. Legro RS. Polycystic ovary syndrome: current and future treatment paradigms. Am J Obstet Gynecol 1998;179(Suppl):101-8
8. Tsilchorozidou T, Overton C, Conway GS. The pathophysiology of polycystic ovary syndrome. Clin Endocrinol (Oxf) 2004;60:1-17
9. Balen AH. Is metformin the treatment of choice for anovulation in polycystic ovary syndrome? Nat Clin Pract Endocrinol Metab 2007;3:440-1
10. Poordast T, Alborzi T, Askari E, Samsami A, Najib FS, Hamedi M, Naghmeh Sanj Z. A Rare Case of Tubo-Ovarian Abscess by Enterococcus SPP, Following Intrauterine Insemination. Int. J. Pharm. Phyto pharm. Res. 2019;9(2):32-5. Polycystic Ovary Syndrome: A woman’s guide to identifying and managing PCOS, Dr. John Eden; 2005:3.5.
11. Polycystic Ovary Syndrome: A woman’s guide to identifying and managing PCOS, Dr. John Eden; 2005:3.
12. PonJola Coney, Polycystic ovarian disease: current concepts of pathophysiology and therapy, Fertility and Sterility;1984 (42): 667- 680
13. McDonnell R, Hart R. Pregnancy-related outcomes for women with polycystic ovary syndrome. Women’s Health, 2017; 13(3): 89-97.
14. Sadeeqa S, Mustafa T, Latif S. Polycystic ovarian syndrome–related depression in adolescent girls: A Review. J Pharm And Bioall Sci., 2018; 10(2): 55
15. Kamalanathan S, Sahoo J, Sathyapalan T. Pregnancy in polycystic ovary syndrome. Indian Endocrinal Metab, 2013; 17(1): 37.
16. Witchel SF, Teede HJ, Peña AS. Curtailing PCOS. Pediatr Res (2020) 87 (2):353–61. doi: 10.1038/s41390-019-0615-1
17. Wilson K. Obesity: Lifestyle Modification and Behaviour Interventions. FP Essent (2020) 492:19–24.
18. Jin P, Xie Y. Treatment Strategies for Women With Polycystic Ovary Syndrome. Gynecol Endocrinol (2018) 34(4):272–7. doi: 10.1080/09513590.2017.1395841
19. Park YJ, Shin HA-O, Jeon S, Cho IA-O, Park HJ. Development and Effects of College- Based Lifestyle Modification Program for Menstrual Health of Young Adult Women With Irregular Menses: A Randomized Controlled Trial. Int J Environ Res Public Health (2020) 18(1):233. doi: 10.3390/ijerph18010233
20. Zeinab Faghfoori, Siavash Fazelian, Mahdi Shadnoush and Reza Goodarzi. Nutritional Management in Women with Polycystic Ovary Syndrome: A Review Study, Diabetes & Metabolic Syndrome. Clin Res Rev. 2017;11(1):S429-S432. doi: https://doi.org/10.1016/j.dsx.2017.03.030.
21. Li L, Feng Q, Ye M, He Y, Yao A, Shi K. Metabolic Effect of Obesity on Polycystic Ovary Syndrome in Adolescents: A Meta-Analysis. J Obstet Gynaecol (2017) 37(8):1036–47. doi: 10.1080/01443615.2017.1318840
22. Kim CA-O, Chon SJ, Lee SH. Effects of Lifestyle Modification in Polycystic Ovary Syndrome Compared to Metformin Only or Metformin Addition: A Systematic Review and Meta-Analysis. Sci Rep (2020) 10(1):7801. doi: 10.1038/s41598-020-64776-w
23. Naderpoor N, Shorakae S, de Courten B, Misso ML, Moran LJ, Teede HJ. Metformin and Lifestyle Modification in Polycystic Ovary Syndrome: Systematic Review and Meta- Analysis. Hum Reprod Update (2015) 21 (5):560–74. doi: 10.1093/humupd/dmv025
24. Steinberg Weiss M, Roe AH, Allison KC, Dodson WC, Kris-Etherton PM, Kunselman AR, et al. Lifestyle Modifications Alone or Combined with Hormonal Contraceptives Improve Sexual Dysfunction in Women with Polycystic Ovary Syndrome. Fertil Steril (2021) 115(2):474–82. doi: 10.1016/ j.fertnstert.2020.08.1396
25. Farshchi H, Rane A, Love A, Kennedy RL. Diet and Nutrition in Polycystic Ovary Syndrome (PCOS): Pointers for Nutritional Management. J Obstet Gynaecol (2007) 27(8):762–73. doi: 10.1080/01443610701667338
26. Otto-Buczkowska E, Grzyb K, Jainta N. Polycystic Ovary Syndrome (PCOS) and the Accompanying Disorders of Glucose Homeostasis Among Girls at the Time of Puberty. Pediatr Endocrinol Diabetes Metab (2018) 24(1):40–4. doi: 10.18544/PEDM-24.01.0101
27. Woodward A, Broom D, Dalton C, Metwally M, Klonizakis M. Supervised Exercise Training and Increased Physical Activity to Reduce Cardiovascular Disease Risk in Women with Polycystic Ovary Syndrome: Study Protocol for a Randomized Controlled Feasibility Trial. Trials (2020) 21(1):101. doi: 10.1186/s13063-019-3962-7
28. Stepto NK, Hiam D, Gibson-Helm M, Cassar S, Harrison CL, Hutchison SK, et al. Exercise and Insulin Resistance in PCOS: Muscle Insulin Signalling and Fibrosis. Endocr Connect (2020) 9(4):346–59. doi: 10.1530/EC-19-0551
29. Escobar-Morreale HF. Polycystic Ovary Syndrome: Definition, Aetiology, Diagnosis and Treatment. Nat Rev Endocrinol (2018) 14(5):270–84. doi: 10.1038/nrendo.2018.24
30. Barrea LA-OX, Arnone A, Annunziata GA-OX, Muscogiuri G, Laudisio DAO, Salzano C, et al. Adherence to the Mediterranean Diet, Dietary Patterns and Body Composition in Women with Polycystic Ovary Syndrome (PCOS). Nutrients (2019) 11(10):2278. doi: 10.3390/nu11102278
31. Rodriguez Paris VA-O, Solon-Biet SA-OX, Senior AA-O, Edwards MC, Desai R, Tedla N, et al. Defining the Impact of Dietary Macronutrient Balance on PCOS Traits. Nat Commun (2020) 11(1):5262. doi: 10.1038/s41467-020-19003-5
32. Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, et al. Recommendations from the International Evidence-Based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. Fertil Steril (2018) 110(3):364–79. doi: 10.1016/j.fertnstert.2018.05.004
33. Moran LJ, Brown WJ, McNaughton SA, Joham AE, Teede HJ. Weight Management Practices Associated With PCOS and Their Relationships With Diet and Physical Activity. Hum Reprod (2017) 32(3):669–78. doi: 10.1093/humrep/dew348
34. Jiskoot GA-O, Timman R, Beerthuizen A, Dietz de Loos A, Busschbach J, Laven J. Weight Reduction Through a Cognitive Behavioural Therapy Lifestyle Intervention in PCOS: The Primary Outcome of a Randomized Controlled Trial. Obes (Silver Spring) (2020) 28(11):2134–41. doi: 10.1002/oby.22980
35. Panidis D, Tziomalos K, Papadakis E, Vosnakis C, Chatzis P, Katsikis I. Lifestyle Intervention and Anti-Obesity Therapies in the Polycystic Ovary Syndrome: Impact on Metabolism and Fertility. Endocrine (2013) 44(3):583– 90. doi: 10.1007/s12020-013- 9971- 5
36. Teede HJ, Joham AE, Paul E, Moran LJ, Loxton D, Jolley D, et al. Longitudinal weight gain in women identifed with polycystic ovary syndrome: results of an observational study in young women. Obesity. 2013;21(8):1526–32.
37. Saleem F, Rizvi SW. New Therapeutic Approaches in Obesity and Metabolic Syndrome Associated with Polycystic Ovary Syndrome. Cureus (2017) 9(11): e1844. doi: 10.7759/cureus.1844
38. Di Segni C, Silvestrini A, Fato R, Bergamini C, Guidi F, Raimondo S, et al. Plasmatic and Intracellular Markers of Oxidative Stress in Normal Weight and Obese Patients with Polycystic Ovary Syndrome. Exp Clin Endocrinol Diabetes (2017) 125(8):506–13. doi: 10.1055/s-0043-111241
39. Akbarzadeh S, Ghasemi S, Kalantarhormozi M, Nabipour I, Abbasi F, Aminfar A, et al. Relationship Among Plasma Adipokines, Insulin and Androgens Level as Well as Biochemical Glycemic and Lipidemic Markers With Incidence of PCOS in Women With Normal BMI. Gynecol Endocrinol (2012) 28(7):521–4. doi: 10.3109/09513590.2011.650747
40. Sam SA-O, Ehrmann DA. Pathogenesis and Consequences of Disordered Sleep in PCOS. Clin Med Insights Reprod Health (2019) 3(13):13. doi: 10.1177/ 117955811987126
41. Simon S, Rahat H, Carreau AM, Garcia-Reyes Y, Halbower A, Pyle L, et al. Poor Sleep Is Related to Metabolic Syndrome Severity in Adolescents With PCOS and Obesity. J Clin Endocrinol Metab (2020) 105(4):e1827–34. doi: 10.1210/clinem/dgz285
42. Chen X, Kong L, Piltonen TT, Gissler M, Lavebratt C. Association of Polycystic Ovary Syndrome or Anovulatory Infertility With Offspring Psychiatric and Mild Neurodevelopmental Disorders: A Finnish Population-Based Cohort Study. Hum Reprod (2020) 25(10):2336–47. doi: 10.1093/humrep/deaa192
43. Tasali E, Van Cauter E, Ehrmann DA. Relationships Between Sleep Disordered Breathing and Glucose Metabolism in Polycystic Ovary Syndrome. J Clin Endocrinol Metab (2006) 91(1):36–42. doi: 10.1210/ jc.2005-1084
44. Damone AL, Joham AE, Loxton D, Earnest A, Teede HJ, Moran LJ. Depression, Anxiety and Perceived Stress in Women With and Without PCOS: A Community-Based Study. Psychol Med (2019) 49(9):1510–20. doi: 10.1017/S0033291718002076
45. Brutocao C, Zaiem F, Alsawas M, Morrow AS, Murad MH, Javed A. Psychiatric Disorders in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta- Analysis. Endocrine (2018) 62(2):318–25. doi: 10.1007/s12020-018-1692-3
46. Kolhe JV, Chhipa AS, Butani S, Chavda V, Patel SA-O. PCOS and Depression: Common Links and Potential Targets. Reprod Sci (2021). doi: 10.1007/s43032- 021-00765-2
47. Patil Anushree D, Vaidya Rama A, Pathak Satish D, Chauhan Sanjay L, Surve Suchitra V, Kokate Pratibha P, Joshi Beena N. Yoga Therapy: The Fourth Dimension in the Multidisciplinary Management of Women with Polycystic Ovary Syndrome, A Narrative Review. Indian Pract 2019;71(4):45-51.
48. Dei Laxmipriya & Verma, Anjali & Dhiman, Kamini. Management of PCOS: A Psychosomatic Disorder by Yoga Practice. Int J Innov Research develop. 2015; 4:216-19.
49. Ratnakumari ME, Manavalan N, Sathyanath D, Ayda YR, Reka K (2018). Study to Evaluate the Changes in Polycystic Ovarian Morphology after Naturopathic and Yogic Interventions. Int J yoga 2018;11(2):139–47. doi: https://doi.org/10.4103/ijoy.IJOY_62_16
50. Patel Vishesha, Heather Menezes, Christian Menezes, Stephanie Bouwer, Chevelta A. BostickSmith, Diana L. Speelman. Mindful Yoga Practice as a Method to Improve Androgen Levels in Women with Polycystic Ovary Syndrome: A Randomized, Controlled Trial. J Am Osteopath Assoc. 2020;120(5):323-35. doi:10.7556/jaoa.2020.050