Volume : 10, Issue : 08, August – 2023

Title:

06.A REVIEW OF RIGHT VENTRICULAR ECHOCARDIOGRAPHIC PARAMETERS IN COVID-19 PATIENTS AND RELATION WITH DISEASE OUTCOMES

Authors :

Rabia Syed, Khawaja Talha Aziz, Abid Ali, Maqbool Ilahi, Muhammad Zarar Khan, Atta Ullah

Introduction: Coronavirus Disease 2019 (COVID-19) primarily manifests with respiratory symptoms. However, it leads to increased mortality due to multi-organ involvement, among which the cardiovascular system is of paramount importance in determining the mortality and morbidity of COVID-19 patients. Echocardiography plays a crucial role in assessing cardiac function in COVID-19 patients. Our objective is to discuss the echocardiographic findings related to the right ventricle and their significance in the clinical outcomes of COVID-19 patients.
Methodology: We conducted a systematic search in PubMed, Scopus, and Google Scholar databases. A total of 8 studies were selected for review. We included original studies published between 2020 and 2022. Only studies involving hospitalized COVID-19 patients were considered.
Results: We identified 9 studies related to the echocardiographic evaluation of cardiac manifestations. Right ventricular alterations were examined in these studies, and the findings were categorized under the headings of anatomical and functional parameters of the right ventricle. The studies reported increased mortality in association with abnormal TAPSE and sPAP. RV-FAC was associated with increased admissions to the ICU. Among the anatomical parameters of the right ventricle, an increase in RVD was linked to increased mortality.
Conclusion: This review suggests that identifying echocardiographic parameters related to COVID-19 is crucial. Alterations in the functional parameters of echocardiography have greater prognostic value than anatomical parameters. Targeting such parameters will help avoid unnecessary investigations.
Key Words: Covid-19, cardiac dysfunction, corona, Echocardiography, Right ventricle

Cite This Article:

Please cite this article in press Rabia Syed et al, A Review Of Right Ventricular Echocardiographic Parameters In Covid-19 Patients And Relation With Disease Outcomes, Indo Am. J. P. Sci, 2023; 10 (08).

Number of Downloads : 10

References:

1. Tudoran C, Tudoran M, Lazureanu VE, Marinescu AR, Pop GN, Pescariu AS, et al. Evidence of pulmonary hypertension after SARS-CoV-2 infection in subjects without previous significant cardiovascular pathology. Journal of Clinical Medicine. 2021;10(2):199.
2. Carrizales-Sepúlveda EF, Vera-Pineda R, Flores-Ramírez R, Hernández-Guajardo DA, Pérez-Contreras E, Lozano-Ibarra MM, et al. Echocardiographic manifestations in COVID-19: a review. Heart, Lung and Circulation. 2021;30(8):1117-29.
3. Baycan OF, Barman HA, Atici A, Tatlisu A, Bolen F, Ergen P, et al. Evaluation of biventricular function in patients with COVID-19 using speckle tracking echocardiography. The international journal of cardiovascular imaging. 2021;37(1):135-44.
4. Zeng J-H, Wu W-B, Qu J-X, Wang Y, Dong C-F, Luo Y-F, et al. Cardiac manifestations of COVID-19 in Shenzhen, China. Infection. 2020;48:861-70.
5. Cameli M, Pastore MC, Soliman Aboumarie H, Mandoli GE, D’Ascenzi F, Cameli P, et al. Usefulness of echocardiography to detect cardiac involvement in COVID‐19 patients. Echocardiography. 2020;37(8):1278-86.
6. Kirkpatrick JN, Mitchell C, Taub C, Kort S, Hung J, Swaminathan M. ASE statement on protection of patients and echocardiography service providers during the 2019 novel coronavirus outbreak: endorsed by the American College of Cardiology. Journal of the American college of cardiology. 2020;75(24):3078-84.
7. Johri AM, Galen B, Kirkpatrick JN, Lanspa M, Mulvagh S, Thamman R. ASE statement on point-of-care ultrasound during the 2019 novel coronavirus pandemic. Journal of the American Society of Echocardiography. 2020;33(6):670-3.
8. Barman HA, Atici A, Tekin EA, Baycan OF, Alici G, Meric BK, et al. Echocardiographic features of patients with COVID-19 infection: a cross-sectional study. The International Journal of Cardiovascular Imaging. 2021;37:825-34.
9. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. European Heart Journal-Cardiovascular Imaging. 2015;16(3):233-71.
10. Fichet J, Moreau L, Genée O, Legras A, Mercier E, Garot D, et al. Feasibility of right ventricular longitudinal systolic function evaluation with transthoracic echocardiographic indices derived from tricuspid annular motion: a preliminary study in acute respiratory distress syndrome. Echocardiography. 2012;29(5):513-21.
11. Mahmoud-Elsayed HM, Moody WE, Bradlow WM, Khan-Kheil AM, Senior J, Hudsmith LE, et al. Echocardiographic findings in patients with COVID-19 pneumonia. Canadian Journal of Cardiology. 2020;36(8):1203-7.
12. Liu Y, Xie J, Gao P, Tian R, Qian H, Guo F, et al. Swollen heart in COVID‐19 patients who progress to critical illness: a perspective from echo‐cardiologists. ESC heart failure. 2020;7(6):3621-32.
13. Chaturvedi H, Issac R, Sharma SK, Gupta R. Progressive left and right heart dysfunction in coronavirus disease-19: Prospective echocardiographic evaluation. European Heart Journal-Cardiovascular Imaging. 2022;23(3):319-25.
14. Huang S, Vignon P, Mekontso-Dessap A, Tran S, Prat G, Chew M, et al. Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study (the ECHO-COVID study). Intensive Care Medicine. 2022;48(6):667-78.
15. Jansson S, Blixt PJ, Didriksson H, Jonsson C, Andersson H, Hedström C, et al. Incidence of acute myocardial injury and its association with left and right ventricular systolic dysfunction in critically ill COVID-19 patients. Annals of Intensive Care. 2022;12(1):56.
16. Valenzuela ED, Mercado P, Pairumani R, Medel JN, Petruska E, Ugalde D, et al. Cardiac function in critically ill patients with severe COVID: A prospective cross-sectional study in mechanically ventilated patients. Journal of Critical Care. 2022;72:154166.
17. Stöbe S, Richter S, Seige M, Stehr S, Laufs U, Hagendorff A. Echocardiographic characteristics of patients with SARS-CoV-2 infection. Clinical Research in Cardiology. 2020;109:1549-66.
18. Sun X, Zhang H, Aike B, Yang S, Yang Z, Dong L, et al. Tricuspid annular plane systolic excursion (TAPSE) can predict the outcome of isolated tricuspid valve surgery in patients with previous cardiac surgery? Journal of Thoracic Disease. 2016;8(3):369.
19. Bieber S, Kraechan A, Hellmuth JC, Muenchhoff M, Scherer C, Schroeder I, et al. Left and right ventricular dysfunction in patients with COVID-19-associated myocardial injury. Infection. 2021;49:491-500.
20. Pagnesi M, Baldetti L, Beneduce A, Calvo F, Gramegna M, Pazzanese V, et al. Pulmonary hypertension and right ventricular involvement in hospitalised patients with COVID-19. Heart. 2020;106(17):1324-31.
21. Deng Q, Hu B, Zhang Y, Wang H, Zhou X, Hu W, et al. Suspected myocardial injury in patients with COVID-19: evidence from front-line clinical observation in Wuhan, China. International journal of cardiology. 2020;311:116-21.
22. Chung M, Bernheim A, Mei X, Zhang N, Huang M, Zeng X, et al. CT imaging features of 2019 novel coronavirus (2019-nCoV). Radiology. 2020;295(1):202-7.
23. D’Andrea A, Martone F, Liccardo B, Mazza M, Annunziata A, Di Palma E, et al. Acute and chronic effects of noninvasive ventilation on left and right myocardial function in patients with obstructive sleep apnea syndrome: a speckle tracking echocardiographic study. Echocardiography. 2016;33(8):1144-55.