Volume : 10, Issue : 12, December – 2023
Title:
DESIGN AND CHARACTERIZATION OF THE ZALTOPROFEN LOADED SOLID LIPID NANO PARTICLES
Authors :
K.Janaki , P.Deepika , D.Varun , P.Venkatesh , S.K.Godasu
Abstract :
The aim of the study was Design and prepare and characterization of the Zaltoprofen loaded solid lipid nano particles. Structure and plan and portrayal of the Zaltoprofen stacked strong lipid nano particles The chitosan is utilized as polymer. The nano particles is planned by applying by nano precipitation technique. After definition improvement the assessment boundaries played out totally went under the scope of limits. The medication discharge the advanced detailing F8 was seen as 99.76%.The motor profile performed for streamlined plan they follow the zero request and higuchi condition. The security reads did for 90 days there is no corruption in streamlined definition in tranquilize delivery and medication content examinations.
Keywords: Design, Charecterization, Zaltoprofen, Solid Lipid Nano Particles
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Cite This Article:
Please cite this article in press K.Janaki et al., Design And Characterization Of The Zaltoprofen Loaded Solid Lipid Nano Particles, Indo Am. J. P. Sci, 2023; 10 (12).
Number of Downloads : 10
References:
[1] Holmes D. The next big things are tiny. Lancet Neurol 2013; 12(1): 31-2.
[2]Re F, Gregori M, Masserini M. Nanotechnology for neurodegenerative disorders. Maturitas 2012; 73(1): 45-51. [http://dx.doi.org/10.1016/j.maturitas.2011.12.015] [PMID: 22261367]
[3] Youns M, Hoheisel JD, Efferth T. Therapeutic and diagnostic applications of nanoparticles. Curr Drug Targets 2011; 12(3): 357-65. [http://dx.doi.org/10.2174/138945011794815257] [PMID: 20955146]
[4] Uchegbu IF. Pharmaceutical nanotechnology: polymeric vesicles for drug and gene delivery. Expert Opin Drug Deliv 2006; 3(5): 629-40. [http://dx.doi.org/10.1517/17425247.3.5.629] [PMID: 16948558]
[5] Farokhzad OC. Nanotechnology for drug delivery: The perfect partnership. Expert Opin Drug Deliv 2008; 5(9): 927-9. [http://dx.doi.org/10.1517/17425247.5.9.927] [PMID: 18754745]
[6] Sun Y, Kang C, Wang M, Zhu J, Jin L, Cheng X. Nanosized camptothecin conjugates for single and combined drug delivery. Eur J BioMed Res 2016; 2: 8-16. [http://dx.doi.org/10.18088/ejbmr.2.1.2016.pp8-14]
[7] Müller RH, Mäder K, Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art. Eur J Pharm Biopharm 2000; 50(1): 161-77. [http://dx.doi.org/10.1016/S0939-6411(00)00087-4] [PMID: 10840199]
[8] Mehnert W, Mäder K. Solid lipid nanoparticles: production, characterization and applications. Adv Drug Deliv Rev 2001; 47(2-3): 165-96. [http://dx.doi.org/10.1016/S0169-409X(01)00105-3] [PMID: 11311991]
[9] Severino P, Andreani T, Macedo AS, Fangueiro JF, Santana MH, Silva AM, et al. Current state-of-art and new trends on lipid nanoparticles(SLN and NLC) for oral drug delivery. J Drug Del 2012; 2012: 750891.
[10] Brunton LL, Hilal-Dandan R, Knollmann BC. eds (2018). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics (13th ed.). McGraw-Hill Education. (ISBN 978-1-25-958473-2)