Volume : 11, Issue : 04, April – 2024
Title:
SYNTHESIS AND BIOLOGICAL ACTIVITIES OF QUINOLINES
Authors :
K. Neelaveni*, Akkenapelli Sri Tejaswini, Allakonda Teena, Bandela Sai Ram, Dr. T. Ramarao
Abstract :
Quinoline, a N-based aromatic compound has numerous applications in various industries, including pharmaceuticals, agrochemicals, dyestuffs, and materials. It has antiprotozoal, antitubercular, anticancer, antipsychotics, anti-inflammatory, antioxidant, anti-HIV, antifungal, efflux pump inhibitors, neurodegenerative diseases and lupus treatment. Quinine and quinidine alkaloids from Cinchona bark contain quinoline scaffolds, making it a key component in clinically used drugs. Various methods have been developed to synthesize quinoline derivatives, including the Gould-Jacob quinoline synthesis, Friedlander quinoline synthesis, Pfitzinger quinoline synthesis, Skraup/Doebner-von Miller quinoline synthesis, and Combes/Conrad-Limpach synthesis.
Keywords; Agrochemicals, Cinchona, cyclodehydration, hypotensive effects, rheumatoid arthiritis
Cite This Article:
Please cite this article in press K. Neelaveni et al, Synthesis And Biological Activities Of Quinolines.,Indo Am. J. P. Sci, 2024; 11 (4).
Number of Downloads : 10
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