Volume : 10, Issue : 12, December – 2023

Title:

ANTHELMINTIC ACTIVITY OF ETHANOLIC EXTRACT OF JATROPHA CURCAS ROOT

Authors :

N. Dhanushiya, V. Dillibabu, M. Dinesh Kumar, M. Perumal, Dr. J. Karthi

Abstract :

Despite the availability of several allopathic medicines, a large number of people continue to rely on nature, which has bestowed upon humans an abundance of medicinal plants for both illness prevention and treatment. The mechanism of action of anthelmintic medications is to either kill or immobilize the parasite so that the host’s immune system can eradicate it. Since the currently available anthelmintics, like albendazole and mebendazole, show several negative effects, including elevated liver enzyme and hematological effects, etc., the current study looked into the plant Jatropha curcas, which is claimed to be useful as an anthelmintic but hasn’t been scientifically validated. The phytochemical studies on the root of Jatropha curcas were carried out to demonstrate its importance as a valuable medicinal plant. The extract was subjected to preliminary phytochemical analysis. The preliminary screening reveals the presence of alkaloids, flavonoids, saponins, steroids, tannins, and triterpenoids. Studies involving the ethanolic root extract of Jatropha curcas were conducted in vitro in pharmacology. Worm paralysis time was used to measure anthelmintic activity. As a result, the study’s findings indicate that Jatropha curcas roots have strong anthelmintic action.
Keywords: Jatropha curcas, Anthelmintic activity, Euphorbiaceae.

Cite This Article:

Please cite this article in press N. Dhanushiya et al., Anthelmintic Activity Of Ethanolic Extract Of Jatropha Curcas Root,Indo Am. J. P. Sci, 2023; 10 (12).

Number of Downloads : 10

References:

1. Pal SK, Shukla Y. Herbal medicine: current status and the future. Asian pacific journal of cancer prevention. 2003 Aug 20;4(4):281-8. Pal SK, Shukla Y. Herbal medicine: current status and the future. Asian pacific journal of cancer prevention. 2003 Aug 20;4(4):281-8.
2. B. Ravishankar. Indian systems of Medicine. Afr J Tradit complement Altern Med. 2007; 4(3): 319-337.
3. Zollman C, Vickers AJ, Richardson J, editors. ABC of complementary medicine. John Wiley & Sons; 2009 Apr 15.
4. World Health Organization. WHO guidelines on developing consumer information on proper use of traditional, complementary and alternative medicine. World Health Organization; 2004
5. Ashfaq UA, Masoud MS, Nawaz Z, Riazuddin S. Glycyrrhizin as antiviral agent against Hepatitis C Virus. Journal of translational medicine. 2011 Dec;9(1):1-7.
6. Subedi CK, Chaudhary RP, Kunwar RM, Bussmann RW, Paniagua-Zambrana NY.
Jatropha curcas L.
7. Riayatsyah TM, Sebayang AH, Silitonga AS, Padli Y, Fattah IM, Kusumo F, Ong HC, Mahlia TM. Current progress of Jatropha curcas commoditisation as biodiesel feedstock: A comprehensive review. Frontiers in Energy Research. 2022 Jan 14;9:1019.
8. Kumar A, Rai A, Khan MS, Kumar A, Haque Z, Fazil M, Rabbani G. Role of herbal medicines in the management of patients with COVID-19: A systematic review and meta- analysis of randomized controlled trials. Journal of traditional and complementary medicine. 2022 Jan 11.
9. Noviana E, Indrayanto G, Rohman A. Advances in Fingerprint Analysis for Standardization and Quality Control of Herbal Medicines. Frontiers in Pharmacology. 2022;13.
10. Patil PS, Shettigar R. An advancement of analytical techniques in herbal research. Journal of Advanced Scientific Research. 2010 Aug 10;1(01):8-14
11. Sembulingam K, Sembulingam P. Essentials of Medical Physiology. 3rded. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2004. p. 176-79.
12. Monteiro MV, Bevilaqua CM, Morais SM, Machado LK, Camurça-Vasconcelos AL, Campello CC, Ribeiro WL, Mesquita MD. Anthelmintic activity of Jatropha curcas L. seeds on Haemonchus contortus. Veterinary parasitology. 2011 Dec 15;182(2-4):259-63.