Volume : 10, Issue : 07, July – 2023
Title:
08.ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION THIOCOLCHICOSIDE AND ACECLOFENAC IN PHARMACEUTICAL DOSAGE FORM BY RP-HPLC
Authors :
Killari Divya Rekha*, Mr. A. Venkateswara Rao, Mrs. B. Sravanasree
Abstract :
The estimation of Thiocolchicoside and Aceclofenac was done by RP-HPLC. The mobile phase was optimized with consists of ACN : Phosphate buffer (pH-4.6) mixed in the ratio of 60:40 % v/ v. A Xterra column C18 (4.6 x 150mm, 5m) or equivalent chemically bonded to porous silica particles was used as stationary phase. The solutions were chromatographed at a constant flow rate of 1.0 ml/min. The linearity range of Thiocolchicoside and Aceclofenac were found to be from 1-5ppm, 25-125g/ml respectively. Linear regression coefficient was not more than 0.999, 0.999.
Keywords: Thiocolchicoside, Aceclofenac, RP HPLC
Cite This Article:
Please cite this article in press Killari Divya Rekha et al, Analytical Method Development And Validation For Simultaneous Estimation Thiocolchicoside And Aceclofenac In Pharmaceutical Dosage Form By RP-HPLC., Indo Am. J. P. Sci, 2023; 10 (07).
Number of Downloads : 10
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