Volume : 10, Issue : 06, June – 2023
Title:
19.ANTI-OXIDANT AND ANTI-PYRETIC ACTIVITY OF HYDROALCOHOLIC EXTRACT OF CASSIA AURICULATA
Authors :
Farheen Bano, Mr Manoj Kumar Sahu, Dr. Jitendra Banweer
Abstract :
The aim of present research work is evaluate antioxidant and antipyretic activity of hydroalcoholic extract of cassia auriculata. Cassia auriculata commonly known as Tanner’s Cassia is an important medicinal shrub used in traditional systems of medicine. Subcutaneous injection of sterilized brewer’s 20 % yeast suspended in 9.0 % in saline at the dose of 1 mL/100 g body weight in albino rat leads to pyrexia. The results conclude that the extract of Cassia auriculata exhibited significant antipyretic activity. While Antioxidant activity of hydroalcoholic extract of Cassia auriculata was used as a conventional compound with ascorbic acid. Free radical hydrogen peroxide scavenging activity (percent) has been calculated.
Keywords: Pyrexia, Estimation, Phytoconstituents, Extraction, Percentage yield
Cite This Article:
Please cite this article in press Farheen Bano et al, Antioxidant And Antipyretic Activity Of Hydroalcoholic Extract Of Cassia Auriculata., Indo Am. J. P. Sci, 2023; 10 (06).
Number of Downloads : 10
References:
1. Chattopadhyay,D., Arunachalam, G., Ghosh, L., Rajendran, A.B. & Bhattacharya, S.K. (2005) Antipyretic activity of Alstonia macrophylla Wall. exA. DC: An ethnomedicine of Andaman Islands. Journal of Pharmacy and Pharmaceutical Sciences, 8, 558–564.
2. Saper, C.B. & Breder, C.D. (1994) The neurologic basic of fever. New England Journal of Medicine, 330, 1880–1886 [DOI: 10.1056/NEJM19940630330260 9] [PubMed: 7832832].
3. Veugelers, P.J., Kaldor, J.M., Strathdee, S.A., Page-Shafer, K.A., Schechter, M.T., Coutinho, R.A., Keet, I.P. & van Griensven, G.J. (1997) Incidence and prognostic significance of symptomatic primary human immuno deficiency virus type Infection in homosexual men. Journal of Infectious Diseases, 176, 112–117[DOI: 10.1086/514012]. Frequency and diagnosis(1992).Family Practice, 9263–9269 [PubMed: PubMed].
4. Baucher, R. (2001) Green-Hernandez CedSingleton JKedAronzon DZed Fever: Approach to the febrile child Primary Care pediatrics. Philadelphia på Lippincott Williams & Wilkins, 343–357.
5. Guton, H. Human Physiology and Mechanisms of Disease, 6th edn. Philadelphia, Pa WB Saunders1997.
6. Baraff LJBass JWFleisher GR et al. Agency for Health Care Policy and Research, Practice guideline for management of infants and children 0 to 36 months of age with fever without source (1993). Annals of Emergency Medicine, 221198–221210.
7. Rajani, G.P., Gupta, D., Sowjanya, K. & Sahithi, B. (2011) Screening of antipyretic activity of aerial parts of Nelumbo nucifera gaertn in yeast induced pyrexia. Pharmacologyonline, 1, 1120–1124.
8. Duraisankar, M. & Ravichandran, V. (2012) Antipyretic potential of polyherbal ayurvedic products. Asian Journal of Pharmaceutical and Clinical Research, 5, 146–150.
9. Gupta, M., Shaw, B.P. & Mukerjee, A. (2008) Studies on antipyretic analgesic and ulcerogenic activity of polyherbal preparation in rats and mice. International Journal of Pharmacology, 4, 88–94.
10. Luheshi, G.N. (1998) Cytokines and fever. Mechanisms and sites of action. Annals of the New York Academy of Sciences, 856, 83–89 [DOI: 10.1111/j.1749-6632.1998.tb08316.x] [PubMed: 9917868].
11. Gomathi, P., Mazumder, U.K. & Gupta, M. (2011) Antipyretic potential of Galega pupurea root. International Research Journal of Pharmacy, 2, 151– 152.
12. Adesokan, A.A., Yakubu, M.T., Owoyele, B.V., Akanji, M.A., Soladoye, A.O. & Lawal, O. (2008) Effect of administration of aqueous and ethanol extracts of Enantia chlorantha stem bark on brewer’s yeast induced pyresis in rats. African J. of Biochemistry, 2, 165–169.
13. Taïwe, G.S., Bum, E.N., Talla, E., Dimo, T., Weiss, N., Sidiki, N., Dawe, A., Moto, F.C., Dzeufiet, P.D. & De Waard, M. (2011) Antipyretic and antinociceptive effects of Nauclea latifolia roots decoction and possible mechanisms of action. Pharmaceutical Biology, 49, 15–25 [DOI: 10.3109/13880209.2010.492479] [PubMed: 20822326].
14. Farnsworth, N.R. (1988) Screening plants for new medicines. In: Biodiversity (edited by E. O. Wilson). National Acaddemic Press: Washington, DC, USA, pp. 83–97.