Volume : 10, Issue : 11, November – 2023
Title:
RECENT RESEARCH ON THE ROLE OF VIRAL INFECTION AS A CAUSE AND SPEED UP THE PROGRESSION OF ALZHEIM’R’S DISEASE
Authors :
Dhiraj A. Thaddani *, Vivek D. Rathod , Sejal R. Sahu,Aniket P. Sawsakade, Pallavi Atalkar , Dipti Damodar , Shreyash S. Padmawar
Abstract :
Alzheimer’s disease (AD) is a progressive neurodegenerative disease for which only symptomatic treatments are available, other than the recently FDA-approved aducanumab. This lack of effective treatment necessitates the study of alternative pathways that may contribute to disease development. Given the recent SARS-CoV-2 pandemic and the troubling neurological complications observed in some patients, the onset and/or progression of microbial viral infections may have an impact on Alzheimer’s disease. It is desirable to (re)examine the feasibility of the theory. Here we review key evidence for this theory, with a particular focus on his two viruses: HSV-1 and SARS-CoV-2. Additionally, we discuss the possible involvement of extracellular vesicles (EVs). This review will contribute to a more rational approach to possible treatment strategies for Alzheimer’s disease patients.
Key words: AD, neurodegenerative disorder, aducanumab, viral infection, HSV-1 and SARS-CoV-2.
Cite This Article:
Please cite this article in press Dhiraj A. Thaddani et al, Recent Research On The Role Of Viral Infection As A Cause And Speed Up The Progression Of Alzheim’r’s Disease, Indo Am. J. P. Sci, 2023; 10 (11).
Number of Downloads : 10
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