Volume : 11, Issue : 02, February – 2024

Title:

CONDUCTOMETRY- ARTICLE REVIEW

Authors :

E.Nagadeepthi*, B.Vamshi Krishna, B.Jhansi,B.V.Ramana

Abstract :

Conductometry is based on the principle of determination of change in conductivity that is the movement of cations towards the cathode and the movement of anions towards the anode.The electric conductance in accordance with Ohms law which states that the strength of current I passing through the conductor is directly proportional to potential difference and inversly to resistance. The movement of the ions mainly depends on the concentration of the ions.It is a method of quantitative analysis used to identify the concentration of a given analyte in a mixture Conductometric titration(ALPHA -06) involves the continuous addition of a reactant to a reaction mixture.The electrolytic conductivity is associated with the changing concentrations of the two most highly conducting ions-the hydrogen and hydroxyl ions.Conductometry is used to analyze ionic species and monitor a chemical reaction by studying the electrolytic conductivity of the reacting species. It is suitable for coloured solutions. It is used to check the alkalinity of the fresh water, to check water pollution in lakes and rivers ,to determine the purity of solution. The End point was determined accurately and errors were minimized as the end point was graphically determined,The temperature was maintained constant throughout the titration.
Keywords: Electrical conductivity, Ohms law , Conductometric titration, Qualitative analysis, End point

Cite This Article:

Please cite this article in press E.Nagadeepthi et al., Conductometry- Article Review, Indo Am. J. P. Sci, 2024; 11 (02).

Number of Downloads : 10

References:

1.Gurdeep.R.Chatwal, sham k. anand, nstrumental method of chemical analysis ,Himalaya publishing house,2008,p.no.2.482-2.497.
2.Hovert H.willard,lynne L.merritt,john A.dean,frank A.settle,jr.,instrumental method of analysis CBS publishers 1986,p.no.732-750.
3.Kenneth A. connors,e textbook of pharmaceutical analysis,third edition,wiley india,p.no. 3. .Danniel christein,analytical chemistry,2nd edition,wiley india,p.no. 274.
4.Ashour, S.;Chehna, F.;Bayram, R. Spectrophotometric determination ofalfuzosin hydrochloride in pharmaceutical preparations with some sulphonepthelein dyes. Int. J. Biomed. Sci. 2006, 2, 273-278
5.Usiu, B. Voltammetric analysis of alfuzosin HCI in pharmaceuticals, human serum and simulated gastricjuice. Electroanalysis, 2002, 14, 866-870. Wiesner, JL; Sutherland, F.C.W.; Van Essen, G.H.; Hundt, H.KL; Swart, K.J.; Hundt, F. Selective, sensitive and rapid liquid chromatography-tandem mass spectrometry method for the determination of alfuzosin in human plasma. J. Chromatogr B. 2003, 788, 361-368.
6.Carlucci, G.; Di-Giuseppe, E.; Mazzeo, P. Determination of alfuzosin in human plasma by high- performance liquid chromatography with column-switching. J. Liq. Chromatogr. 1994, 17, 3989-3997.
7.Rouchouse, A.; Manoha, M.; Durand, A.; Thénot, J.P. Direct high-performance liquid chromatographic determination of the enantiomers of alfuzosin in plasma on a second-generation alphal-acid glycoprotein chiral stationary phase. J. Chromatogr. A. 1990, 506, 601-610
8.Krstulovic, A.M.; Vende, JL. Improved performance of the second generation alphal-AGP columns: applications to the routine assay of plasma levels of alfuzosin hydrochloride, Chirality. 1989, 1, 243-245.
9.Guinebault, P.; Broquaire, M.; Colafranceschi, C.; Thénot, J.P. High-performance liquid chromatographic determination of alfuzosin in biological fluids with fluorimetric detection and large-volume injection. J. Chromatogr. A. 1986, 353, 361-369.
10.Rashedi, H., Norouzi, P., Ganjali, M.R. Determination of alfuzosin by hybrid of ionic liquid graphene nano- composite film using coulometric FFT linear sweep voltammetry. Int. J. Electrochem. Sci. 2013, 8, 2479- 2490
11.Zarapkar, S.S., Bhandari, N.P.; Halkar, U.P. Simultaneous determination of fexofenadine
hydrochloride and pseudoephedrine sulfate in pharmaceutical dosage by reverse phase high performance liquidchromatography. Indian Drugs. 2000, 37, 421-425.
12.Radhakrishna, T.; Reddy, G.O. Simultaneous determination of fexofenadine and its related compounds by HPLC. 1. Pharm. Biomed. Anal. 2002, 29, 681-690.Breier, A.R., Paim, S.C.; Menegola, J.;Steppe, M.; Schapoval, E.E. Development and validation of a liquid
13.chromatographic method for fexofenadine hydrochloride in capsules. J. AOAC Int. 2004, 87, 1093-1097.
14.Kozan, L; Palabiyik, L.M.; Karacan, E.; Onur, F. Spectrophotometric and high performance liquid chromatographic determination of fexofenadine hydrochloride in pharmaceutical formulations, Turk Pharm. Sci. 2008, 5, 175-189.
15.Vekaria, H.; Limbasiya, V.; Patel, P. Development and validation of RP-HPLC method for simultaneous estimation of montelukast sodium and fexofenadine hydrochloride in combined dosage form.
16.Karakuş, S., Küçükgüzel, L; Güniz Küçükgüzel, Ş. Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binarypharmaceutical dosage forms. J. Pharm. Biomed. Anal. 2008, 46, 295-302
17.Arayne, M.S.; Shehnaz, H.; Sultana, N.; Haider, A. RP-HPLC method for the quantitative determination of fexofenadine hydrochloride in coated tablets and human serum. Med. Chem. Res, 2011, 20, 55-61.