Volume : 11, Issue : 05, May – 2024
Title:
SYNTHESIS, CHARACTERIZATION AND ANTI-MICROBIAL ACTIVITY OF 2,5DIMETHYL PYRROLE
Authors :
Venkat Reddy. R*, Neha Jabeen, Deepika Gundeboina, Syed Waliullah Hussain, Dr. CH.V. Suresh, Dr. K. N Venkateswara Rao
Abstract :
Aim: Synthesis of some pyrrole derivatives from condensation of acetonylacetone with ammonium carbonate Yields the 2,5 Dimethyl pyrrole and evaluate the potential antimicrobial activity.
Method: Reflexation of acetonylacetone with ammonium carbonate with the support of oil bath at 100 °Caround 60 minutes on cooling reaction mixture.The yellow layer is separated and extracted with chloroform on evaporation of chloroform we yield product .
Result:This molecules exhibits moderate to good antimicrobial activity .Which are comparable to standards used in this study.
Conclusion:The result of 2,5 Dimethylpyrrole indicates that a number of this molecules exhibits moderate to good antibacterial ,antifungal activities and this class of compounds as potential leads towards antimicrobial agents .
Keywords: Dimethylpyrrole,Reflux,Antimicrobial.
Cite This Article:
Please cite this article in press Venkat Reddy . R et al, Synthesis, characterization, and anti-microbial Activity of 2,5dimethyl pyrrole.,Indo Am. J. P. Sci, 2024; 11 (5).
Number of Downloads : 10
References:
1. Abdul Rauf, Himani Varshney,Aiman Ahmad,Fohad M.Husain ,Iqbal Ahmad Synthesis and anti microbial evalutation of fatty chain substituted 2,5 di methyl pyrrole and 1,3- benzoxazine-4-one derivatives ; volume 21,January 2017,Pages 394-402.
2. Jitendra D.Bhosale,Amey R.Shirolkar,Umesh D.Pete,Chetan M.Zade ,Dipesh p Synthesis ,characterisation and biological activites of novel substituted formazans of 3,4- di methyl-1H-Pyrrole -2-carbohydrazide derivatives; August, 2013,Pages 582-587.
3. Akbar Idhayadhulla,Radha Krishnan Surendara Kumar,and Abdul Jamal Nasser Synthesis ,characterisation and antimicrobial activity of new pyrrole derivative ;August 2011,Pages 218-223.