Volume : 11, Issue : 05, May – 2024
Title:
ROLE OF HERBAL PROKINETICS IN TREATMENT OF FUNCTIONAL DYSPEPSIA
Authors :
Shayestha Nishath, Sameera Taranum, Safoora Naaz, Madiha Naazish, Shaista Tamkanat
Abstract :
Dyspepsia, a common gastrointestinal disorder characterized by upper abdominal discomfort. Its etiology includes gastric predisposition, GERD, peptic ulcer disease, H pylori infection, gastric malignancy, and various physiological and psychological mechanisms such as impaired gastric motility, visceral hypersensitivity, delayed gastric emptying, impaired gastric accommodation, central nervous system dysfunction etc. Although dyspepsia is not related to increased mortality, but it may impact the patient quality of life by causing complications like chronic indigestion, anxiety and depression. The conventional pharmacological treatment includes use of proton pump inhibitors, dopamine-2 receptor antagonists, antidepressants, prokinetic agents etc. But the conventional treatment often come with limitations and potential adverse effects such as nausea, diarrhea etc. Some conventional prokinetic drugs, particularly those like metoclopramide, can aggravate stomach discomfort or cause gastric irritation in some individuals, while herbal prokinetics on the other hand may be kind on the stomach and less likely to exacerbate dyspeptic symptoms.
Hence, the alternative and complementary therapies are considered for the treatment of dyspepsia such as herbal prokinetics, derived from various plants offers promising effects for modulating gastrointestinal motility and reducing symptoms associated with dyspepsia.
The herbal prokinetics may be considered a better choice than conventional prokinetics in the treatment of dyspepsia, because of their minimal side effects, effectiveness in reducing the symptoms such as gastric discomfort and various other advantages over the conventional prokinetic agents.
By exploring various treatment options and comparing the safety and efficacy of herbal prokinetics and conventional prokinetics, this review critically examines the mechanism of action of various herbal prokinetics and evaluates the available clinical evidence supporting their efficacy and safety in dyspepsia management.
This review article aims to show the advantages of using herbal prokinetics over conventional prokinetics and their contribution in improving patient’s quality of life without causing serious adverse effects.
While herbal prokinetics offer these potential benefits, it’s important to recognize that responses to herbal prokinetics can vary from person to person, and their effectiveness and safety may not be fully confirmed through various clinical trials.
Key Words:Dyspepsia, Herbal prokinetics, Conventional prokinetics
Cite This Article:
Please cite this article in press Shayestha Nishath et al., Role Of Herbal Prokinetics In Treatment Of Functional Dyspepsia., Indo Am. J. P. Sci, 2024; 11 (05).
Number of Downloads : 10
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